Researchers may have discovered why certain antipsychotic medications, such as those used to treat schizophrenia, lead to extreme weight gain. A study published in the “Proceedings of the National Academy Of Sciences” suggests that these drugs increase the activity of the enzyme AMPK in the parts of the brain that regulate eating behavior.
Patients taking the antipsychotic drugs olanzapine (sold under the brand name Zyprexa by Eli Lilly and Co.) and clozapine (sold as Clorazil by Novartis AG) have been known to gain so much weight that they are placed at increased risk for obesity-related disorders such as diabetes and cardiovascular disease.
“Their use has been hampered primarily by the fact that for some of them there is this horrible gain, largely due to just eating too much from increased appetite,” said Dr. Solomon Snyder, a professor of neuroscience at Johns Hopkins School of Medicine, where the study was based.
“It’s a big increase and it occurs with very little doses of the drug,” he said.
The results of the study, which involved experimentation on mice, suggest that the antipsychotics interfere with the protein histamine, leading to an increase in AMPK activity. Histamine is an important actor in local immune responses — including allergy symptoms — that has long been suspected to play a role in controlling weight.
Snyder expressed hope that the new study’s findings could aid in the development of antipsychotic drugs to do not lead to weight gain.
“Unfortunately, Zyprexa, which everybody agrees is the best therapeutic agent, gives the worst weight gain, along with clozapine, the parent drug in the class,” he said.
But consumer advocate Mike Adams, Mike Adams, author of “How to Halt Diabetes in 25 Days,” instead took the results as a sign of the inherent risks of psychiatric drugs.
“We’ve known for a long time that antipsychotic drugs cause severe blood sugar imbalances and even increase the risk of diabetes,” Adams said
“Now scientists are pinpointing the biochemical mechanism by which these drugs cause massive weight gain, an average of 22 pounds in the first year. That’s enough to make anyone depressed — which, of course, often leads to stronger, more dangerous drugs being prescribed. As a result, antipsychotic drugs actually create their own repeat revenue by keeping patients depressed and overweight.”
David Gutierrez


Related Posts
Like this:
Like Loading...
Related
Published by dreddymd
Dr Eddy Bettermann MD focus on Biological Medicine (Biologische Medizin), Darkfield Microscopy (Dunkelfeld Mikroskopie), Orthomolecular Medicine (Orthomolekulare Medizin), Ayurvedic Medicine (Ayurveda), Psychosomatic Medicine (Psychosomatische Medizin), raw food (Rohkost), fasting (Fasten):
Our primary integrative medicine goal is the maintenance of your health and wellness, and we are committed to safe and effective healthcare.
Our specialties include online integrative medicine education by alternative doctor: food and allergy management through the use of Integrative medical therapy, Environmental Medicine, General Family Medicine, Ayurveda, Panchakarma, Chronic Fatigue, ADHD, autism, Fibromyalgia, Yeast/Fungus related diseases – Candidacies, mercury dental replacement and detoxification, Natural Thyroid Replacement, Weight loss, Lyme Disease, Irritable Bowel Disease, Attention Deficit Disorder, Pervasive Developmental Disorders, Multiple Chemical Sensitivities, Addiction related programs, Intestinal Dysbiosis, as well as trigger point therapy using Neural Therapy.
Dr. Eddy Bettermann MD, physician from Germany, consultant and teacher in biological medicine, especially dark field microscopy known as Live Blood Analysis in Thailand, Malaysia, Hong Kong, Singapore and the Philippines. But he lecture also in the USA, Canada and the U.A.E. He speaks english and german.
https://dreddymd.com/2017/01/17/the-interactive-live-blood-cd-and-the-certified-training-live-blood-analysis-online-course/
https://dreddymd.com/courses/
https://dreddymd.com/2017/01/17/live-blood-microscopy-analysis-darkfield-course/
“Let thy Food be thy Medicine and thy Medicine be thy Food.” — Hippocrates
Physician Member of the Medical Board at AOX Singapore,
Medical Doctor at Nurse Mobile Clinic and
Physician at DrEddy Clinic
Our Mission:
The mission of the Integrative Medicine is to search for the most effective treatments for patients by combining both conventional and alternative approaches that address all aspects of health and wellness – biological, psychological, social and spiritual. Biological Medicine is a big part of my work and so is Dark field Microscopy, what I use in my daily practice and what I teach more then 15 years in Asia and around the world: Live Blood Analysis in dark field based on Haematology.
We utilize Live blood analysis since 2004, conventional as well as specialty laboratories for a thorough diagnostic work up of the disease in question. Our integrative medicine treatment regimens are especially unique and are tailored specifically to the individual needs of each patient.
Our Mission: don’t harm, prevent, use food as medicine
We are a reliable partner for integrative medicine in Medical Spa & Clinic Development and integrative medicine Education Training for alternative doctors – we bring different holistic approaches, like Integrative Medicine, Traditional Chinese Medicine and Ayurveda Medicine together. On your request we offer our service in your place as well.
Heavy metal poisoning
Heavy metal poisoning is much more common than most people realize, and if you’re thinking that it doesn’t apply to you because you haven’t been exposed to any, think again. If you’ve eaten fish regularly, had amalgam fillings, received vaccinations, drank contaminated water, or done industrial or agricultural work or pharmaceutical manufacturing, there’s a good chance that you have a fair amount of toxic metals in your system..
We are here to help and to educate!
Wishing your health and happiness
Dr Eddy Bettermann MD
Multimedia library https://bit.ly/2Wgqsd3
Protect you and your family from harmful radiation https://bit.ly/synergyscience-dreddymd
More information about 5G and EMF: https://dreddymd.com/?s=5G+and+EMF
Protocol https://amzn.to/2Nxsfql
View all posts by dreddymd