Histone Modifications Reveal Further Insight into the Process of Aging

Epigenetic research on the potential molecular causes of aging has piqued the curiosity of many people who want to know if it’s possible to slow aging or, perhaps, stop it altogether. The process of aging comes along with physiological changes that decrease the body’s ability to repair tissue and increase vulnerability to metabolic diseases. Overall, … Continue reading Histone Modifications Reveal Further Insight into the Process of Aging

Bisphenol A Can Reprogram Liver’s Epigenome and Result in Disease in Rats

There has been growing literature that suggests how environmental chemical exposure can lead to birth defects but the majority of the studies are association based. A fraction of those studies have shown how ambient chemical exposure affects insulin sensitivity and lipid metabolism1  or affecting gut-microbiota2. But how early life chemical exposure can affect epigenetics—or change the epigenome … Continue reading Bisphenol A Can Reprogram Liver’s Epigenome and Result in Disease in Rats

The Epigenetics Behind Unique Human Faces

Here’s a strange question many people probably have not given much thought to: why are our faces shaped the way they are? We know that no two faces are perfectly alike, but why exactly might one person have a long nose and another a small forehead? How is it that our earlobes are attached to … Continue reading The Epigenetics Behind Unique Human Faces

Histone Modifications and Epigenetic Regulation Could Hold the Key to Reversing Aging

Epigenetics has numerous connections to the process of aging, research hinting at the association between longevity and factors such as transcriptome length and DNA methylation patterns. Clearly, understanding the molecular controls of aging proves to be an intriguing endeavor as we try to interpret the clues of how we might slow down and perhaps even reverse aging. … Continue reading Histone Modifications and Epigenetic Regulation Could Hold the Key to Reversing Aging

Could Common Chemicals Tip the Epigenetic Balance and Program Someone for Obesity?

We’ve all heard of the risks of the BPA, or Bisphenol A, a chemical used to make durable plastics. BPA can be found in baby bottles, toys, water bottles, and the lining of food cans, but it has also leached into the water and air, travelling around the world. Research has shown this endocrine disruptor can … Continue reading Could Common Chemicals Tip the Epigenetic Balance and Program Someone for Obesity?

Epigenetics of Breastfeeding: 4 Diseases and Disorders That Breast Milk Could Protect Against

Many people believe that breastfeeding is the best gift a mother can offer to her child. It has lots of benefits, not only because breast milk contains the right amount of nutrients, but also because it’s packed with lots of antibodies and biologically active compounds that play a key role in boosting a baby’s immune … Continue reading Epigenetics of Breastfeeding: 4 Diseases and Disorders That Breast Milk Could Protect Against

The Epigenetic Landscape is a Key Determinant of Gene Expression Reprogramming in Cardiac Hypertrophy

The epigenetic signature for cardiac hypertrophy, which can progress to heart failure through an adaptive response of the myocardium to stress, is still poorly understood. The scientists at Humanitas Clinical and Research Center, Rozzano, Italy report on the genome-wide distribution of seven histone modifications in adult mouse cardiomyocytes subjected to a prohypertrophy stimulus in vivo. They found … Continue reading The Epigenetic Landscape is a Key Determinant of Gene Expression Reprogramming in Cardiac Hypertrophy

Epigenetic Study of Histone Modifications and DNA Damage Could Lead to New Cancer Treatments

DNA damage occurs frequently to cells as a result of normal cellular processes, but one of the worst genetic malfunctions that can occur is DNA double-strand breaks, or DSBs. This can lead to cancer and increased resistance to cancer therapy. New research from scientists at The University of Texas MD Anderson Cancer Center reported their … Continue reading Epigenetic Study of Histone Modifications and DNA Damage Could Lead to New Cancer Treatments