Silymarin from milk thistle can prevent hand-foot syndrome, a common side effect of chemotherapy, reports study
Silymarin, the active ingredient in milk thistle (Silybum marianum), is a flavonoid commonly used to treat liver disorders. But a recent study suggests that silymarin can also be used to reduce the harmful side effects of chemotherapy.
In a recent study, researchers from Mashhad University of Medical Sciences (MUMS) in Iran found that topical application of silymarin can reduce the severity of hand-foot syndrome (HFS), a common side effect of chemotherapy. It is characterized by inflammation of the palms and soles.
Moreover, their study revealed that topical application of silymarin can also delay the onset of HFS in cancer patients. Their findings appeared in the journal Phytotherapy Research.
Silymarin for the prevention and treatment of HFS
HFS, or palmar-plantar erythrodysesthesia, is a skin reaction that occurs upon exposure to certain drugs used in chemotherapy. Capecitabine, a chemotherapy medication used to treat breast, gastric and colorectal cancer, is notorious for causing HFS.
For their study, the researchers assessed the preventive effects of silymarin on capecitabine-induced HFS. To this end, the team conducted a randomized, double-blinded clinical trial involving 40 cancer patients who had no prior exposure to capecitabine but were scheduled to be treated with the drug.
Three in four patients in the silymarin group had gastric cancer. The researchers also measured all of the participants’ risk for HFS at baseline.
For the trial, the team placed both groups on capecitabine. They then applied a gel containing one percent silymarin on the soles and palms of patients in the silymarin group twice daily for nine weeks. They also measured the participants’ risk for HFS every three weeks.
The results showed that both groups had a higher risk of HFS during capecitabine treatment. But patients in the silymarin group had a lower risk of HFS at the end of the trial. The team also noted a delay in the development and progression of HFS in the silymarin group.
Taken together, their findings show that topical application of silymarin helps reduce the severity of capecitabine-induced HFS and delay its occurrence in cancer patients undergoing chemotherapy. (Related: ONIONS are just as effective as chemotherapy at beating cancer.)
Silymarin and its medicinal properties
Silymarin in milk thistle is hailed for its hepatoprotective effects. An ancient medicinal plant, milk thistle has been used for centuries to protect the liver from food poisoning and the harmful effects of alcohol abuse.
Several studies on silymarin suggest that the flavonoid can protect the liver from oxidative damage by neutralizing free radicals. Because of this antioxidant activity, silymarin has been studied for its potential in preventing or treating diseases that affect various organs, such as the kidneys, brain and pancreas.
For instance, one animal study found that silymarin helped treat kidney injuries in diabetic rats. This suggests that silymarin can be an effective treatment for diabetic nephropathy, a serious, kidney-related complication of diabetes.
Another study showed that silymarin can reduce protein oxidation in the brains of older rats. Protein oxidation is associated with free radical-induced damage and brain disorders. Other in vivo experiments also showed that silymarin has antidepressant-like effects.
Silymarin is available in the form of milk thistle capsules, tablets, tinctures and intravenous solutions. Taking 420 milligrams (mg) of milk thistle extract — standardized to contain 70 to 80 percent silymarin — per day is considered safe.
Read more articles about milk thistle and other medicinal plants at PlantMedicine.news.
Divina Ramirez
Doctor blows whistle on chemotherapy doesn’t work 97% of the time
Dr Eddy Bettermann MD focus on Biological Medicine (Biologische Medizin) #Biological #Medicine #videos http://bit.ly/2LF3Ro3, Darkfield Microscopy (Dunkelfeld Mikroskopie), Orthomolecular Medicine (Orthomolekulare Medizin), Ayurvedic Medicine (Ayurveda), Psychosomatic Medicine (Psychosomatische Medizin), raw food (Rohkost), fasting (Fasten):
Our primary integrative medicine goal is the maintenance of your health and wellness, and we are committed to safe and effective healthcare.
Our specialties include online integrative medicine education by alternative doctor: food and allergy management through the use of Integrative medical therapy, Environmental Medicine, General Family Medicine, Ayurveda, Panchakarma, Chronic Fatigue, ADHD, autism, Fibromyalgia, Yeast/Fungus related diseases – Candidacies, mercury dental replacement and detoxification, Natural Thyroid Replacement, Weight loss, Lyme Disease, Irritable Bowel Disease, Attention Deficit Disorder, Pervasive Developmental Disorders, Multiple Chemical Sensitivities, Addiction related programs, Intestinal Dysbiosis, as well as trigger point therapy using Neural Therapy.
Dr. Eddy Bettermann MD, physician from Germany, consultant and teacher in biological medicine, especially dark field microscopy known as Live Blood Analysis in Thailand, Malaysia, Hong Kong, Singapore and the Philippines. But he lecture also in the USA, Canada and the U.A.E. He speaks english and german.
https://dreddymd.com/2017/01/17/the-interactive-live-blood-cd-and-the-certified-training-live-blood-analysis-online-course/
https://dreddymd.com/courses/
https://dreddymd.com/2017/01/17/live-blood-microscopy-analysis-darkfield-course/
“Let thy Food be thy Medicine and thy Medicine be thy Food.” — Hippocrates
Physician Member of the Medical Board at AOX Singapore,
Medical Doctor at Nurse Mobile Clinic and
Physician at DrEddy Clinic
Our Mission:
The mission of the Integrative Medicine is to search for the most effective treatments for patients by combining both conventional and alternative approaches that address all aspects of health and wellness – biological, psychological, social and spiritual. Biological Medicine is a big part of my work and so is Dark field Microscopy, what I use in my daily practice and what I teach more then 15 years in Asia and around the world: Live Blood Analysis in dark field based on Haematology.
We utilize Live blood analysis since 2004, conventional as well as specialty laboratories for a thorough diagnostic work up of the disease in question. Our integrative medicine treatment regimens are especially unique and are tailored specifically to the individual needs of each patient.
Our Mission: don’t harm, prevent, use food as medicine
We are a reliable partner for integrative medicine in Medical Spa & Clinic Development and integrative medicine Education Training for alternative doctors – we bring different holistic approaches, like Integrative Medicine, Traditional Chinese Medicine and Ayurveda Medicine together. On your request we offer our service in your place as well.
Heavy metal poisoning
Heavy metal poisoning is much more common than most people realize, and if you’re thinking that it doesn’t apply to you because you haven’t been exposed to any, think again. If you’ve eaten fish regularly, had amalgam fillings, received vaccinations, drank contaminated water, or done industrial or agricultural work or pharmaceutical manufacturing, there’s a good chance that you have a fair amount of toxic metals in your system..
We are here to help and to educate!
Wishing your health and happiness
Dr Eddy Bettermann MD
We are affiliated The Wellness Company https://bit.ly/3V726zc
The Wellness Company Coupon for membership, supplements, doctor appointment, online consultation https://bit.ly/3V5NsIy
DrEddyClinic is affiliate of Amazon and get commission for the products, which we recommend https://www.amazon.com/shop/dreddyclinic , same as GlobalHealing https://dreddymd.com/shop/supplements/
View all posts by dreddymd
Silymarin, the active ingredient in milk thistle (Silybum marianum), is a flavonoid commonly used to treat liver disorders. But a recent study suggests that silymarin can also be used to reduce the harmful side effects of chemotherapy.
Dr. Eddy Bettermann MD 