While trans-pterostilbene may not be familiar, its sources–blueberries and grapes–certainly are. Like its cousin resveratrol, plants produce pterostilbene in response to injury and infection. Also like resveratrol, pterostilbene has a high level of bioavailability and offers similar protective effects. Additionally, research suggests pterostilbene may be more powerful than resveratrol. In fact, combining pterostilbene with resveratrol may pack a potent nutritional punch, helpful for supporting healthy cellular function.
4 Benefits of Pterostilbene
Blueberries are one of the most readily-available sources of pterostilbene and are typically available year round. Wine also contains varying levels of this powerful compound. Here are 4 more reasons to add pterostilbene to your diet.
1. Potent Antioxidant
Experiments suggest pterostilbene has several important benefits. First and foremost, the compound acts as a powerful antioxidant. It also appears to bind to PPAR receptors, stimulating production of the compound. PPAR plays an important role regulating cholesterol and lipids in the blood. One study using animal models reported its success promoting normal triglyceride levels. 
2. Supports Normal Blood Sugar
Numerous studies have found blueberry consumption, particularly pterostilbene ingestion, supports already healthy blood sugar. In one study, 97 adults took a pterostilbene supplement for 12 weeks. At the end of the study, 67% of the participants had normal glucose levels. 
3. Rejuvenates Brain Cells
The antioxidant and soothing properties of pterostilbene helps brain cell health. Multiple studies have demonstrated pterostilbene supports motor function and cognitive abilities in adults suffering from memory changes. 
4. Like Red Wine, Pterostilbene Promotes Longevity
Trans-pterostilbene is a bioactive chemical which has been shown to support cognitive health, normal blood sugar, and soothe irritation. In vitro and in vivo studies support pterostilbene’s therapeutic effects. The compound also acts as a caloric restriction mimetic, triggering the human body to release biochemicals such as adiponectin which promotes healing.
Supplementing with Pterostilbene
To get a bigger serving of pterostilbene, you can eat a lot (a lot!) of blueberries, or you could also try a supplement. Most supplements will use trans-pterostilbene for its high bioavailability. If you opt to take a supplement, I highly recommend Cell Fuzion™, a potent blend of antioxidants and powerful ingredients, including Pterostilbene. Cell Fuzion helps protect and energize mitochondrial function and protect against oxidative stress.
by Dr. Edward Group DC, NP, DACBN, DCBCN, DABFM
- Cignarella A1, Nastasi M, Cavalli E, Puglisi L. Novel lipid-lowering properties of Vaccinium myrtillus L. leaves, a traditional antidiabetic treatment, in several models of rat dyslipidaemia: a comparison with ciprofibrate. Thromb Res. 1996 Dec 1;84(5):311-22.
- ICMR. Flexible dose open trial of Vijayasar in cases of newly-diagnosed non-insulin-dependent diabetes mellitus. Indian Council of Medical Research (ICMR), Collaborating Centres, New Delhi. Indian J Med Res. 1998 Jul;108:24-9.
- Denise McCormack 1 and David McFadden. A Review of Pterostilbene Antioxidant Activity and Disease Modification. Oxid Med Cell Longev. 2013; 2013: 575482.