Chanca Piedra, Gallstones, and Kidney Stones
Chanca Piedra has been used by the indigenous peoples of the Amazon for generations to support the elimination of gallstones and kidney stones. In Ayurvedic medicine, chanca piedra is thought to hold the most promise against kidney stone formation.  Although longer-term randomized clinical trials are necessary to confirm therapeutic properties, some preliminary studies suggest chanca piedra may indeed have potential to provide defense against kidney stones.  This may be due to reducing the formation of obstructions in the gallbladder and kidneys. A 2002 study in India found that Chanca Piedra helps to increase bile secretion of the liver. Extra bile helps the digestion process, this benefits nutrient absorption and waste elimination. In fact, we are so convinced of the benefits of chanca piedra for gallstones and kidney stones that we decided to use it in Renaltrex® and our liver cleanse product Livatrex®.
Chanca Piedra and the Liver
Traditional Chinese medicine has always cited chanca piedra as an herb for liver health support.  In a test involving mice, The Department of Chemistry at Bose Institute in India investigated the liver protecting action of chanca piedra against acetaminophen toxicity and their results showed that a protein in chanca piedra protected liver tissues against oxidative stress, probably by increasing antioxidative defenses.  Study results from the Patel Institute of Pharmaceutical Education and Research suggest compounds in chanca piedra may be a valuable component to a multiple herb, liver-protection formulation. 
Antioxidant Activity of Chanca Piedra
Chanca piedra has been tested for antioxidant activity and response to high blood pressure and high blood sugar. The high phenolic content of chanca piedra has shown antioxidant activity, which has been found to support balanced blood sugar and optimal blood pressure levels.    This has some excited about the effect of chanca piedra during times of distress. In one study, when put to the test against chemically induced skin tumors, researchers noted that chanca piedra engages an enhanced antioxidant defense system. 
Actions Against Harmful Organisms
Water extracts of chanca piedra have shown toxic activity against types of harmful organisms, without affecting beneficial organisms.  The Universidad de la República studied 28 plant and algae species for activity against harmful organisms. Researchers noted that the most interesting activity was observed in chanca piedra.  This observation and conclusion was duplicated by researchers at the University of Malaysia. 
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